Influence of Lycium barbarum Extract Intake on Oxidative Stress in Wistar Rats
Braz. arch. biol. technol
; 65: e22210114, 2022. tab, graf
Article
in En
|
LILACS-Express
| LILACS
| ID: biblio-1364452
Responsible library:
BR1.1
ABSTRACT
Abstract This study aimed to analyze the effects of Goji Berry extract (GB, Lycium barbarum) gavage administration on liver tissue oxidative stress in Wistar rats as well as to identify and quantify the content of the major bioactive compounds of the fruit. Four diets were applied SW - standard diet + water; SG - standard diet + Goji Berry extract (125 mg/kg of animal); PW - palatable diet + water; PG - palatable diet + Goji Berry extract (125 mg/kg of animal). Results showed a significant increase in catalase enzyme activity in the liver of rats treated with GB and also in those intaking the palatable diet without GB when compared to the SW group. An increased mRNA expression of this enzyme in the same tissue and groups was also verified. Regarding lipid peroxidation, the GB extract produced a significant decrease in the oxidation state in the SG and PG groups. The results also showed a significant amount of bioactive compounds in GB extract.
Full text:
1
Collection:
01-internacional
Database:
LILACS
Language:
En
Journal:
Braz. arch. biol. technol
Journal subject:
BIOLOGIA
Year:
2022
Document type:
Article
Affiliation country:
/